Four Points You Need To Know About Calcium Carbonate

April 11,2022

Calcium carbonate is widely used in clinic. There are at least four things you have to know about it.


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Calcium content of calcium carbonate


Due to the acid environment of human stomach, there is almost no difference in the absorption rates of insoluble calcium carbonate and calcium citrate and soluble calcium acetate, calcium lactate and calcium gluconate. Normal people should try to choose carbonic acid with high calcium content (40%).


Infant gastric juice is nearly neutral and should not take calcium carbonate. It is recommended to choose calcium gluconate and calcium acetate that can be absorbed without being decomposed by gastric acid. After 2 ~ 3 years old, the concentration of gastric acid gradually increases, and calcium carbonate with rich calcium content can be selected.


Clinical use of calcium carbonate


Calcium carbonate is not only a common calcium supplement, but also an antacid, and can be used in hyperphosphatemia.


Calcium carbonate combines with phosphate in the gastrointestinal tract to form insoluble complex and reduce phosphate absorption. It can be used to treat renal osteodystrophy, hyperphosphatemia and secondary hyperparathyroidism caused by chronic renal failure.


Adverse reaction of calcium carbonate


Overdose can cause high blood calcium. Hypercalcemia is usually caused by injection, but it can also occur when oral administration is not appropriate, especially for patients with renal failure or taking vitamin D at the same time.


The symptoms of hypercalcemia include anorexia, nausea, vomiting, stomach pain, muscle weakness, constipation, thirst, irritability, polyuria, renal calcinosis, kidney stones, and even arrhythmia and coma.


When to take calcium carbonate?


Calcium is best taken between meals and 1 hour after dinner. Plant foods contain more fatty acids and oxalic acids, which can combine with calcium ions to form insoluble calcium salts, which is not conducive to calcium absorption.


Calcium carbonate, as an antacid, can also be taken before going to bed. Many people have experienced muscle twitching, and usually in sleep. However, there is still a lack of evidence of calcium supplementation in the treatment of painful muscle spasm.